InpharmD™





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What is InpharmD™?


Literature searching is tedious. InpharmD™ is here to help.

Clinical pharmacists can ask any question, anytime, from anywhere, and we’ll perform a custom literature search.

(And a 32% chance it’s already been asked.)


15,708

Clinical Pharmacist Hours Saved

4x +

ROI

100%

Clinical Pharmacist Satisfaction Rate

This is how InpharmD™ transforms LITERATURE.

What's Being Asked...

Is there any method to measure the percentage of calcium absorptions in the individual after using the dietary supple...
Establishment of intestinal homeostasis during the neonatal period
Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease
Counting the dead in Gaza: difficult but essential
The interplay between host immune cells and gut microbiota in chronic inflammatory diseases?

What would you like to ask InpharmD™?

InpharmD™'s Answer GPT's Answer

Author: Neil Patel, PharmD, BCPS + InpharmD™ AI

INTRODUCTION BY INPHARMD™ RESEARCHER

Stroke is one of the leading causes of disability worldwide. Aphasia among stroke survivors is common. Current speech and language therapy (SLT) strategies have only limited effectiveness in improving aphasia. A possible adjunct to SLT for improving SLT outcomes might be non-invasive brain stimulation by transcranial direct current stimulation (tDCS) to modulate cortical excitability and hence to improve aphasia. We included only randomised controlled trials (RCTs) and randomised controlled ...

In patients who underwent surgery, four prognostic factors, including age, T stage, number of positive lymph nodes, and radiation, were selected into nomogram development for predicting postoperative OS. C-index, decision curve analyses, integrated discrimination improvement, and time-dependent receiver operating characteristics showed better performance in nomogram than in the tumor-node-metastasis staging system. Calibration plots demonstrated good consistency between nomogram predicted survival and actual observed survival. The patients were stratified into three different risk groups by prognostic scores and Kaplan-Meier curves showed significant difference between these groups. In patients who underwent surgery, four prognostic factors, including age, T stage, number of positive lymph nodes, and radiation, were selected into nomogram development for predicting postoperative OS. C-index, decision curve analyses, integrated discrimination improvement, and time-dependent receive...

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A search of the published medical literature revealed 1 study investigating the researchable question:

Is there any method to measure the percentage of calcium absorptions in the individual after using the dietary supplement?

Level of evidence
B - One high-quality study or multiple studies with limitations  

READ MORE→

1. Ferlay J, Ervik M, Lam F, et al. Global Cancer Observatory: cancer today. International Agency for Research on Cancer; 2020.

InpharmD™'s Answer GPT's Answer

Author: Neil Patel, PharmD, BCPS + InpharmD™ AI

INTRODUCTION BY INPHARMD™ RESEARCHER

The journal Cancers had the highest number of publications, while Cancer Research was the most frequently cited journal. Molecular, biology, immunology, medicine and genetics were the main research disciplines in the field of CAFs. Key directions in CAFs research encompassed the study of transforming growth factor-β, Fibroblast Activation Protein, breast cancer, as well as growth and metastasis. The findings from the analysis of keyword co-occurrence and literature co-citation have revealed s...

Cancer-associated fibroblasts (CAFs) constitute an important component of the tumor microenvironment, participating in various facets of cancer advancement and being recognized as contributors to tumor immune evasion. What are therapeutic alternatives for Azacitidine for Injection? Editing inquiry in android latest build What are therapeutic alternatives for Azacitidine for Injection? Editing inquiry in android latest build What are therapeutic alternatives for Azacitidine for Injection? Editing inquiry in android latest build What are therapeutic alternatives for Azacitidine for Injection? Editing inquiry in android latest build What are therapeutic alternatives for Azacitidine for Injection? Editing inquiry in android latest build. The role of CAFs in various tumor types has attracted increasing attention recently. In this work, we conducted a comprehensive bibliometric analysis to uncover research trajectories and highlight emerging areas in the field of CAFs. What are therapeu...

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A search of the published medical literature revealed 1 study investigating the researchable question:

Establishment of intestinal homeostasis during the neonatal period

Level of evidence
B - One high-quality study or multiple studies with limitations  

READ MORE→

InpharmD™'s Answer GPT's Answer

Author: Neil Patel, PharmD, BCPS + InpharmD™ AI

INTRODUCTION BY INPHARMD™ RESEARCHER

The mammalian intestine is colonized by trillions of microorganisms that have co-evolved with the host in a symbiotic relationship. The presence of large numbers of symbionts near the epithelial surface of the intestine poses an enormous challenge to the host because it must avoid the activation of harmful inflammatory responses to the microorganisms while preserving its ability to mount robust immune responses to invading pathogens. In patients with inflammatory bowel disease, there is a bre...

Millions of agricultural workers  waged and self-employed  while feeding the world, regularly face high levels of working poverty, malnutrition and poor health, and suffer from a lack of safety and labour protection as well as other types of abuse. With low and irregular incomes and a lack of social support, many of them are spurred to continue working, often in unsafe conditions, thus exposing themselves and their families to additional risks. Further, when experiencing income losses, they may resort to negative coping strategies, such as distress sale of assets, predatory loans or child labour. Migrant agricultural workers are particularly vulnerable, because they face risks in their transport, working and living conditions and struggle to access support measures put in place by governments. Guaranteeing the safety and health of all agri-food workers  from primary producers to those involved in food processing, transport and retail, including street food vendors  as well as be...

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A search of the published medical literature revealed 1 study investigating the researchable question:

Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

Level of evidence
B - One high-quality study or multiple studies with limitations  

READ MORE→

InpharmD™'s Answer GPT's Answer

Author: Neil Patel, PharmD, BCPS + InpharmD™ AI

INTRODUCTION BY INPHARMD™ RESEARCHER

The available treatment options for purpura fulminans (PF) include supportive care and comprehensive treatments to curb the underlying cause and manage complex coagulopathy. The most common type of PF is acute infectious PF, occurring with sepsis and requiring appropriate antimicrobials, consideration for IVIG, and management of the underlying coagulopathy. Additional treatments for PF include anticoagulants and replacement of depleted blood and/or factors including protein C concentrate (ava...

Several review articles aimed to discuss the etiology, diagnosis, and management of purpura fulminans (PF) to help guide clinical practice. Purpura fulminans is multifaceted, necessitating prompt diagnosis and comprehensive treatment strategies to curb the underlying cause and manage complex coagulopathy. Initial treatment includes supportive care and adequate hydration. Anticoagulation and replacement of blood, factors, and platelets may be required. Proposed treatments include Protein C (PC) concentrate, heparin, and therapeutic plasma exchange (TPE), all aimed at addressing the underlying coagulopathy. Ceprotin is available as the only PC concentrate in the United States. Cases of infectious PF require broad-spectrum antibiotics and consideration for intravenous immunoglobulin (IVIG) therapy. Medical management emphasizes the importance of timely intervention, leveraging a combination of anticoagulants and supportive therapies to mitigate the severe thrombotic and inflammatory ma...

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A search of the published medical literature revealed 2 studies investigating the researchable question:

What are the available treatment options and supporting evidence to treat Purpura Fulminans in critical ill patients?

Level of evidence
C - Multiple studies with limitations or conflicting results  

READ MORE→

[1] Perera TB, Murphy-Lavoie HM. Purpura Fulminans. In: StatPearls. Treasure Island (FL): StatPearls Publishing; July 17, 2023.
[2] Colling ME, Bendapudi PK. Purpura Fulminans: Mechanism and Management of Dysregulated Hemostasis. Transfus Med Rev. 2018;32(2):69-76. doi:10.1016/j.tmrv.2017.10.001
[3] Chalmers E, Cooper P, Forman K, et al. Purpura fulminans: recognition, diagnosis and management. Arch Dis Child. 2011;96(11):1066-1071. doi:10.1136/adc.2010.199919

InpharmD™'s Answer GPT's Answer

Author: gabrielle pak, PharmD, BCPS + InpharmD™ AI

INTRODUCTION BY INPHARMD™ RESEARCHER

Immunoglobulin (Ig) A controls host-microbial homeostasis in the gut. IgA recognition of beneficial bacteria is decreased in acutely undernourished children, but the factors driving these changes in IgA targeting are unknown. Child undernutrition is a global health challenge that is exacerbated by poor sanitation and intestinal inflammation. To understand how nutrition impacts immune-microbe interactions, we used a mouse model of undernutrition with or without fecal-oral exposure and assessed...

The International Association for the Study of Pain defines chronic pain as any pain lasting longer than three months. There are multiple sources of chronic pain. Combination therapy for pain includes both pharmacological therapies and nonpharmacological treatment options. There is a more significant reduction in pain with combination therapy compared to a single treatment alone. Escalation of pharmacological therapy is in a stepwise approach. Comorbid depression and anxiety are widespread in patients with chronic pain. Patients with chronic pain are also at increased risk for suicide. Chronic pain can impact every facet of a patient's life. Thus learning to diagnose and appropriately manage patients experiencing chronic pain is critical. Significant changes in blood flow or in the integrity of cerebral vessels are believed to cause cerebrovascular disease (CVD) and to contribute to dementias including Alzheimer’s disease [1]. Stroke, the most serious form of CVD, is one of the lead...

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A search of the published medical literature revealed 1 study investigating the researchable question:

The interplay between host immune cells and gut microbiota in chronic inflammatory diseases?

Level of evidence
C - Multiple studies with limitations or conflicting results  

READ MORE→

[1] Imtiaz S, Shield KD, Fischer B, Elton-Marshall T, Sornpaisarn B, Probst C, Rehm J. Recent changes in trends of opioid overdose deaths in North America. Subst Abuse Treat Prev Policy. 2020 Aug 31;15(1):66.
[2] Wang LJ, Xiong J, Liu ST, Pan LL, Yang GX, Hu JF. J Nat Prod. 2015 Jul 24;78(7):1635-46. doi: 10.1021/acs.jnatprod.5b00195. Epub 2015 Jul 1.
[3] Wang LJ, Xiong J, Liu ST, Liu XH, Hu JF. Chem Biodivers. 2014 Jun;11(6):919-28. doi: 10.1002/cbdv.201300283.
[4] Zhang M, Wang JS, Oyama M, Luo J, Guo C, Ito T, Iinuma M, Kong LY. J Asian Nat Prod Res. 2012;14(7):708-12. doi: 10.1080/10...

Find answers, not documents.

Before InpharmD™


BeforeTime
Your team spends hours per week cobbling together literature from different studies, many behind paywalls, leaving little time for action.
BeforeTime
TI opportunities are discovered (or presented by third parties) months after the fact, resulting in costly missed savings.
BeforeTime
Decisions may be made without a complete picture, or pushed out while gathering consensus.

After InpharmD™


BeforeTime
InpharmD™ delivers customized, actionable drug information in real time, so you can focus on execution.
BeforeTime
Your team stays informed immediately when new data emerges or prices change, and you’ll always be the first to know when any changes impact your formulary.
BeforeTime
With InpharmD™, your team can make faster, more informed decisions and move forward with confidence.

What Clinical Pharmacists Are Saying...


     

Assists in our research and is a great way or us to get an answer to a medical question without spending an average of 2 hours researching UptoDate or PubMed ourselves.


  Jordan C., PharmD, New Jersey

     

Huge time saver with thorough responses.


  Jane D., PharmD, Georgia

     

I’d never heard of a DI pharmacist before, now I have one. In. My. Pocket. Amazing!


     

Holy Shhh. Cow! Holy Cow! These summaries are beautiful.


  Jane D., PharmD, Georgia

     

I just want to say: This is such a brilliant idea! You people are genius.


     

OH MY GOD WHERE HAVE YOU BEEN ALL MY LIFE!


     

I can’t tell you how much time I spend literature searching. And how I CANNOT STAND PAYWALLS. THIS IS UNBELIEVABLE!! (covers face for sec) thank you, thank you, thank you!


     

So they’re basically connecting academic researchers with front line providers and then automating everything. It’s simply brilliant.


     

The clinical pharmacist was our our secret weapon anyway. (Smiles wryly) This pharmacist AI seems superhuman. I’m just blown away, honestly. (Looks at camera somberly.)


     

It’s an ENTIRE DI DEPARTMENT, that lives in Epic. Give me a second. I’m just having a hard time wrapping my head around that.


     

Sorry just give me a second, my mind is blown.


     

Wow. . Just wow.


     

Answers are evidence based and help me make clinical decisions. Quick turn around time for some urgent questions.


     

Was bragging about you and your outstanding business the other day while on vacation. I recently used your service and was blown away at how fast and thorough I got your response


     

It would be helpful to provide a discussion of the questions frequently submitted to InpharmD. Other than that it is excellent, please keep it up!


     

A must have resource for evidence based medicine!


     

All information provided is up to date.


     

Provides a good summary of information with citations.


     

Answers clinically relevant questions with quick responses.


     

The review of evidence provided is excellent.


     

I find the vaccination guideline information the most useful.


     

The tables provided from the studies used to formulate the responses are very helpful for review.


     

It is helpful that InpharmD provides indications to treat adverse effects of various drugs in similar classes.


What would you like to ask InpharmD™?

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